The relationship between gut microbiota and neurodevelopmental continuity in very preterm infants
10.3760/cma.j.issn.1673-4408.2025.01.009
- VernacularTitle:极早产儿肠道微生物群与神经发育连续性的关系
- Author:
Wenchao ZHANG
1
;
Liying DAI
Author Information
1. 安徽医科大学附属省儿童医院 安徽医科大学第五临床医学院新生儿科，合肥 230000
- Keywords:
Very preterm infant;
Gut microbiota;
Neurological development;
Brain-gut-microbiome axis
- From:
International Journal of Pediatrics
2025;52(1):43-48
- CountryChina
- Language:Chinese
-
Abstract:
Very preterm infant（VPI）is a high-risk group for gut microbiota dysbiosis and neurodevelopmental disorders.There is a strong link between the gut microbiota and neurodevelopment early in life，especially for VPI，and this link has attracted increasing attention.There is a lack of insight into the mechanisms underlying the microbiota-gut-brain axis（MGBA）in VPI.By studying traumatic diseases，infectious diseases，and different gut flora，it is found that early-life intestinal microbiota abnormalities have an important impact on the host's long-term neurological development.This review focuses on the association between gut microbiota and neurological behavior during early development in VPI，and provide reference for improving neurological development and growth in VPI.
