Progress on the treatment of infantile spasm
10.3760/cma.j.issn.1673-4408.2025.01.008
- VernacularTitle:婴儿痉挛症治疗的研究进展
- Author:
Mingyang YOU
1
;
Fuyan MA
;
Liang HUO
Author Information
1. 中国医科大学附属盛京医院小儿神经内科，沈阳 110004
- Keywords:
Infantile spasm;
Epileptic syndrome;
Refractory epilepsy;
Traditional treatment;
Novel treatment
- From:
International Journal of Pediatrics
2025;52(1):38-42
- CountryChina
- Language:Chinese
-
Abstract:
Infantile spasm is an age-related epileptic encephalopathy，most are drug-resistant，as the chirldren grow older，it will transfer into other epileptic syndrome.Most chirldren have a bad prognosis with neurodevelomental disorders.For now，aderenocortitropic hormone，glucocorticoid and vigabatrin are first-line treatment choice.But the control rate of spasm、remission rate of EEG and recurrence rate after first-line treatment are not ideal.It's necessary to find more effective treatment plans desperately.Considering the diversity and complexity of infantile spasm's etiologies，there are a lot of studies about treatment plan based on etiology.Controlling spasm more effectively，improving prognosis，personalized therapy and targeted therapy become the new focus.This article reviews the current treatment status of infantile spasm，also upates some novel methods which is not widely applied in clinical practice.
