Progress on the relationship between small intestinal bacterial overgrowth and functional gastrointestinal disorders
10.3760/cma.j.issn.1673-4408.2025.01.006
- VernacularTitle:小肠细菌过度生长与功能性胃肠病关系的研究进展
- Author:
Xiaoli FU
1
;
Xuxia WEI
;
Junjie XU
;
Hongling CHEN
;
Le ZHANG
;
Ning XUE
Author Information
1. 山东大学附属儿童医院（济南市儿童医院）消化科 250022
- Keywords:
Small intestinal bacterial overgrowth;
Functional gastrointestinal disorders;
Pathophysiology;
Diagnosis;
Treatment
- From:
International Journal of Pediatrics
2025;52(1):27-32
- CountryChina
- Language:Chinese
-
Abstract:
Small intestinal bacterial overgrowth（SIBO）is a clinically common but poorly recognized disease with clinical symptoms that overlap with those of functional gastrointestinal disorders（FGID）. FGID is a common risk factor for the occurrence of SIBO，and its SIBO incidence rate is significantly higher than that of healthy people，and has a certain correlation. Intestinal microbiota dysbiosis（including SIBO）plays an important role in the pathophysiology of FGID. At present，the diagnosis and treatment of SIBO still face challenges，and the treatment plan of FGID is gradually introduced into the treatment of SIBO. SIBO and FGID are closely related in clinical manifestations，incidence rate，pathophysiology，treatment and other aspects，but there is little research on the relationship between them. Prospective and large-scale clinical research is still needed to improve understanding and diagnostic accuracy.This article reviews the research progress on the relationship between SIBO and FGID.
