Progress on drug treatment for corrosive esophageal stenosis in children
10.3760/cma.j.issn.1673-4408.2025.01.005
- VernacularTitle:儿童腐蚀性食管狭窄药物治疗研究进展
- Author:
Ke QI
1
;
Lingchao ZENG
;
Chunhui WANG
;
Xun JIANG
Author Information
1. 西安医学院研究生工作部 710021
- Keywords:
Children;
Corrosive esophageal stenosis;
Drug
- From:
International Journal of Pediatrics
2025;52(1):22-26
- CountryChina
- Language:Chinese
-
Abstract:
Children who ingest corrosive substances by mistake usually have a small amount of exploratory ingestion，so perforation caused by injury is rare，and emergency surgical treatment is rarely required in the acute stage.But it is very easy to cause esophageal stenosis in the long term.Esophageal stenosis can last for weeks to months，and the children's difficult swallowing can lead to chronic pain in the esophagus and long-term malnutrition.At present，the main clinical treatment is endoscopic esophageal dilation，which requires multiple dilation treatments.The treatment period of corrosive esophageal stenosis in children is long，if supplemented with effective drugs during treatment，it is expected to reduce the degree of esophageal stenosis，reduce the number of dilation，and shorten the treatment period.On the other hand，early administration of protective drugs can promote benign wound healing after esophageal injury.This article reviews the research progress on drug treatment for corrosive esophageal stenosis in children.
