Advances in the application of Lacticaseibacillus rhamnosus GG in pediatric digestive system diseases
10.3760/cma.j.issn.1673-4408.2025.01.001
- VernacularTitle:鼠李糖乳酪杆菌GG在儿童消化系统疾病中的应用进展
- Author:
Gaojie LIU
1
;
Xufei WANG
;
Yizhong WANG
;
Ting ZHANG
Author Information
1. 上海市儿童医院 上海交通大学医学院附属儿童医院消化科 200062
- Keywords:
Children;
Lacticaseibacillus rhamnosus GG;
Digestive system diseases
- From:
International Journal of Pediatrics
2025;52(1):1-5
- CountryChina
- Language:Chinese
-
Abstract:
Lacticaseibacillus rhamnosus GG is one of the most studied probiotic strains,characterized by high acid resistance,high bile salt resistance,and strong adhesion.The main functions of Lacticaseibacillus rhamnosus GG include enhancing intestinal barrier function,inhibiting pathogen adhesion,regulating the body's immune system,which make it effective in treating and preventing gastrointestinal diseases in children and adults.This article reviewes the application research progress of Lacticaseibacillus rhamnosus GG in the treatment of common pediatric digestive system diseases such as necrotizing enterocolitis,infantile colic,non-alcoholic fatty liver disease,inflammatory bowel disease,antibiotic associated diarrhea,irritable bowel syndrome,and acute gastroenteritis in children.