Progress on the role of nitric oxide and hydrogen sulfide in gastrointestinal motility disorder
10.3760/cma.j.issn.1673-4408.2024.12.004
- VernacularTitle:一氧化氮及硫化氢在消化道动力障碍性疾病中的作用研究进展
- Author:
Lijun ZUO
1
;
Zailing LI
Author Information
1. 北京大学第三医院儿科 100191
- Keywords:
Nitric oxide;
Hydrogen sulfide;
Gastrointestinal motility disorder
- From:
International Journal of Pediatrics
2024;51(12):809-813
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal motility disorder is a common disease in the gastroenterology department. Its incidence is increasing year by year，which seriously affects people's quality of life.Its pathogenesis is complex. Nitric oxide（NO）and hydrogen sulfide（H 2S）are two types of gas signaling molecules. NO is an important neurotransmitter in the gastrointestinal nervous system，which is involved in the transmission of nerve signals and thus regulates smooth muscle.H 2S plays an important role in regulating oxidative stress and maintaining cell balance，normal cell activity and body survival.At present，studies on NO and H 2S are gradually emerging.This paper focuses on the relationship between NO and H 2S and four primary dynamic diseases of digestive tract，such as achalasia of cardia，gastroesophageal reflux disease，gastroparesis syndrome，and false intestinal obstruction.
