Research Status of Caenorhabditis elegans Model in Toxicology and Its Applica-tions in Forensic Science
10.12116/j.issn.1004-5619.2024.440406
- VernacularTitle:秀丽隐杆线虫模型毒理学研究现状及其法医学应用前景
- Author:
Zhuo LI
1
;
Yi-Ru ZENG
;
Zhi-Long SHU
;
Xue-Hong SUN
;
Kui ZHANG
Author Information
1. 四川大学华西基础医学与法医学院,四川 成都 610041
- Keywords:
forensic toxicology;
environmental forensic medicine;
Caenorhabditis elegans;
model organism;
review
- From:
Journal of Forensic Medicine
2025;41(2):136-143
- CountryChina
- Language:Chinese
-
Abstract:
Caenorhabditis elegans,as an emerging model organism,has been widely used in multiple disciplines such as medicine,life science,and environmental science in recent years,due to its charac-teristics of short life cycle,clear genetic background,highly conserved evolution,complete genome analysis and excellent fitting between experimental data and human results.It also shows unique advan-tages in the field of toxicology.This paper summarizes its advantages in toxicological research starting from the biological characteristics of C.elegans,introduces the toxicological research methods and progress based on the C.elegans model,focuses on demonstrating its applications in environmental fo-rensic medicine and forensic toxicology,and looks forward to the application of the relevant results in the field of forensic science.
