In Vivo Analysis of New Psychoactive Substances:Nitazenes
10.12116/j.issn.1004-5619.2024.340704
- VernacularTitle:体内尼秦类新精神活性物质的分析
- Author:
Guo-Qing GAO
1
;
Shuo YANG
;
Li-Ying ZHOU
;
Shi-Bei DU
;
Yan SHI
Author Information
1. 司法鉴定科学研究院 上海市法医学重点实验室 司法部司法鉴定重点实验室 上海市司法鉴定专业技术服务平台,上海 200063;中国药科大学药学院,江苏 南京 210009
- Keywords:
forensic medicine;
toxicological analysis;
new psychoactive substance;
nitazenes;
in vivo;
analysis methods;
review
- From:
Journal of Forensic Medicine
2024;40(6):597-607
- CountryChina
- Language:Chinese
-
Abstract:
Nitazenes are a class of synthetic opioids that have recently emerged in the illegal drug market.They are characterized by high potency and a narrow therapeutic window.Compared with tradi-tional opioids,these substances are more likely to cause severe respiratory depression.In recent years,the abuse of nitazenes has occurred frequently,causing hundreds of overdose deaths worldwide,and posing a serious threat to individual health and public safety.As more nitazenes continue to emerge,research on the identification of these substances has received increasing attention.This paper reviews the structural characteristics,in vivo and in vitro pharmacological characterizations and analysis methods of common nitazenes,aiming to provide a basis and reference for the study of these substances in fo-rensic toxicology.
