The Impact of STR Mutations on Kinship Identification
10.12116/j.issn.1004-5619.2024.541008
- VernacularTitle:STR突变对亲缘关系鉴定的影响
- Author:
Jing LIU
1
;
Zheng WANG
;
Yi-Ping HOU
;
Lin-Chuan LIAO
Author Information
1. 四川大学华西基础医学与法医学院,四川 成都 610041
- Keywords:
forensic genetics;
kinship identification;
STR mutation;
genetic marker;
analysis method;
re-view
- From:
Journal of Forensic Medicine
2024;40(5):484-491
- CountryChina
- Language:Chinese
-
Abstract:
Kinship identification is an important field of forensic genetics research,which can be widely applied in inheritance disputes,criminal investigations,and the identification of victims in ma-jor disaster cases.At present,capillary electrophoresis-based STR analysis is still the main method for kinship identification,but the impact of STR mutations on kinship identification needs further explora-tion.This paper reviews the theoretical basis and research status at home and abroad of kinship identi-fication.The challenge of STR mutation impact on kinship identification is prospected,and possible so-lutions are discussed in order to obtain a regular understanding of the impact of STR mutation on kin-ship identification and improve the accuracy of kinship analysis.
