Research Progress of Metal-organic Framework Composites in Drugs Detection
10.19756/j.issn.0253-3820.251242
- VernacularTitle:金属有机框架复合材料在毒品检测中的研究进展
- Author:
Qin-Hong YIN
1
;
Shuo-Ling ZHANG
;
Wei LI
;
Tao-Ren WANG
;
Yan-Qin ZHU
Author Information
1. 云南警官学院禁毒学院,智慧禁毒教育部重点实验室,云南省智慧禁毒重点实验室,昆明 650223
- Keywords:
Metal-organic frameworks;
Composite material;
Drugs detection;
Review
- From:
Chinese Journal of Analytical Chemistry
2025;53(11):1784-1796
- CountryChina
- Language:Chinese
-
Abstract:
Metal-organic frameworks(MOFs)are a class of organic-inorganic hybrid materials formed by the self-assembly of metal ions or metal clusters with organic ligands through coordination,and possess high specific surface area,tunable pore size and diverse structures.In recent years,MOFs and their composites have shown great application potential in the field of drug detection,especially in selective recognition,enhancing detection sensitivity and on-site rapid detection.This paper summarized the structural characteristics,synthesis methods and detection principles of MOFs and their composites,and reviewed the latest research progresses in detection of various drugs such as opioids,amphetamines,cannabinoids,cathinones,cocaine,ketamine,fentanyls and psychotropic drugs.The advantages and challenges of MOFs materials in the pretreatment of complex biological samples,sensor construction and on-site rapid detection were discussed,and the prospects for future development were analyzed,with the aim of providing theoretical support and technical references for promoting the applications of MOFs in anti-drug practice.
