Research Progress on Electrochemical Sensors for Monoamine Neurotransmitters
10.19756/j.issn.0253-3820.241145
- VernacularTitle:单胺类神经递质电化学传感器的研究进展
- Author:
Yu ZHONG
1
;
Yu ZHANG
;
Xiu-Zhi KANG
;
Jing SUN
;
Cheng DONG
;
Hong-Wei WU
;
Yan-Zhao LI
;
Nan LI
Author Information
1. 锦州医科大学附属第一医院重症医学科,锦州 121000;大连大学环境与化学工程学院,大连 116622
- Keywords:
Monoamine neurotransmitter;
Electrochemical sensor;
Electrode material;
In vivo in situ detection;
Review
- From:
Chinese Journal of Analytical Chemistry
2025;53(9):1411-1421
- CountryChina
- Language:Chinese
-
Abstract:
Monoamine neurotransmitters mainly include serotonin,dopamine,epinephrine,and norepinephrine.They play an indispensable regulatory role in key physiological activities such as emotion,sleep,and memory within the central nervous system.Precise detection of these neurotransmitters holds great significance in the field of neuroscience research.Detection methods for monoamine neurotransmitters encompass high-performance liquid chromatography,mass spectrometry,capillary electrophoresis,fluorescence spectroscopy,and electrochemical methods,etc.Compared with other methods,electrochemical methods offer advantages such as high sensitivity,good selectivity,low cost,strong portability,convenient operation,and capability for in vivo real-time detection.This article reviewed recent research progress in electrochemical detection of monoamine neurotransmitters,focusing on a retrospective and summary from three aspects:sensor electrode materials,detection of various monoamine neurotransmitters,and in vivo real-time analysis.Furthermore,the future development of electrochemical sensors for monoamine neurotransmitters was prospected.