Advances in Detection of Common Drugs Based on Surface Enhanced Raman Spectroscopy
10.19756/j.issn.0253-3820.241348
- VernacularTitle:基于表面增强拉曼光谱检测常见毒品的研究进展
- Author:
Jian-Hua LYU
1
;
Jun-Qiu CHEN
;
Chang-Li LYU
Author Information
1. 云南警官学院禁毒学院,智慧禁毒教育部重点实验室,云南省智慧禁毒重点实验室,昆明 650223
- Keywords:
Surface-enhanced Raman spectroscopy;
Complex matrix;
Illicit drug detection;
Review
- From:
Chinese Journal of Analytical Chemistry
2025;53(6):853-863
- CountryChina
- Language:Chinese
-
Abstract:
The number and types of drug abuse are increasing all over the world.The detection of drug suspects and biological samples of drug users plays an important role in forensic medicine.Surface-enhanced Raman spectroscopy(SERS)has the characteristics of fingerprint recognition,high sensitivity,high accuracy,fast and nondestructive,and is not interfered by water molecules.SERS has been widely used in detection of trace drugs and drugs in complex matrices.This paper introduced the types of SERS substrates applied to drug detection and the development status of portable SERS instruments.The research progresses of SERS in drug detection in the past five years were reviewed,focusing on the types of SERS detected drugs,the design of enhanced substrates,detection methods and detection limits.Finally,the application prospect of SERS technology in drug detection was discussed to provide reference for the development of drug detection technology in the future.
