Research Progress of Metal-Organic Frameworks-Aptasensors for Detection of Contaminants in Food and Medicine Homology Substances
10.19756/j.issn.0253-3820.241350
- VernacularTitle:金属有机框架-适配体传感器检测药食同源物质中污染物的研究进展
- Author:
Xing GUO
1
;
Jin-Ju TIAN
;
Xiao-Zhen TANG
;
Xiao-Yue WANG
;
Na SONG
;
Jin-E WANG
;
Chao ZHU
Author Information
1. 德州学院药学院,德州 253023;山东农业大学食品科学与工程学院,泰安 271018
- Keywords:
Food and medicine homology;
Metal-organic frameworks;
Aptasensors;
Contaminants;
Review
- From:
Chinese Journal of Analytical Chemistry
2025;53(4):547-560
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the market share of food and medicine homology substances has continued to grow,and various types of contamination issues have become the focus of attention both inside and outside the industry.The contamination not only affects the original medicinal quality,but also leads to the accumulation of toxic substances in the human body,causing acute and chronic severe hazards such as vomiting,poisoning and cancer.Therefore,the development of biosensors that can conveniently,accurately and sensitively detect various pollutants in food and medicine homology substances has become a research hotspot.Aptasensors based on metal-organic frameworks(MOFs)with advantages such as strong specificity,rapid response and simple operation,have been widely used in detection of various pollutants.This review focused on the research progress of aptasensors based on MOFs for detection of food and medicine homology contamination in the past few years,and provided a detailed comparison and analysis for detection of chemical pollutants(such as pesticide residues,heavy metal residues,mycotoxins,etc.)and microbial contamination in food and medicine homology substances.Besides,the development trend and possible challenges of MOFs aptasensors in detection of food and medicine homology substances in the future were discussed,which was anticipated to provide a reference for the development of new MOFs aptasensors.