Nasal nitric oxide in preschool children with chronic rhinosinusitis
10.16066/j.1672-7002.2025.07.010
- VernacularTitle:鼻一氧化氮测试在学龄前儿童慢性鼻窦炎诊疗中的应用
- Author:
Meiling WU
1
;
Jiewei LIU
;
Ping LIU
;
Rifu WEI
;
Shang GAO
;
Huifeng LI
;
Xiaochun PAN
Author Information
1. 宁德师范学院附属宁德市医院耳鼻咽喉科,福建 宁德 352100
- Keywords:
Nitric Oxide;
Sinusitis;
Child;
nasal nitric oxide
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2025;32(7):451-454
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE Analyze the nasal nitric oxide(NNO)of CRS children,and explore the clinical value of NNO in the diagnosis and treatment of CRS in children.METHODS CRS children diagnosed in the outpatient clinic were selected,and were divided into CRS with and without AR according to their allergen results.VAS score and NNO test were performed for them.Healthy children during the same period were selected as the control group.Finally their results were compared and analyzed.RESULTS The NNO of CRS children with and without AR were(193±62)ppb and(138±49)ppb,both lower than the control group's[(243±51)ppb];There were negative correlations between NNO and VAS scores in CRS children without AR before and after treatment;The NNO of CRS children with and without AR were significantly increased after treatment(P<0.05);NNO has high predictive value for diagnosing CRS children without AR(P<0.01).CONCLUSION The levels of NNO in different types of CRS were lower than normal,and CRS children without AR was lower than those with AR.NNO could assist in the diagnosis of CRS,dynamically reflect the severity of nasal inflammation,and help to distinguish the allergic status of CRS.
