Clinical analysis of periostinoma of the sinonasal glomangiopericytoma
10.16066/j.1672-7002.2025.07.009
- VernacularTitle:鼻腔鼻窦球周皮细胞瘤临床分析
- Author:
Yanhui ZHOU
1
;
Qiongqiong LIU
Author Information
1. 河南科技大学临床医学院,河南科技大学第一附属医院 耳鼻咽喉科,河南 洛阳 471003
- Keywords:
Nasal Cavity;
Paranasal Sinus Neoplasms;
Diagnosis,Differential;
glomangiopericytoma
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2025;32(7):448-450
- CountryChina
- Language:Chinese
-
Abstract:
OBGECTIVE To explore the clinical diagnosis and treatment of sinonasal glomangiopericytoma.METHODS A retrospective analysis was conducted on the clinical data of 6 cases of sinonasal glomangiopericytoma involving the nasal cavity and paranasal sinuses treated in our hospital from October 2010 to December 2024.The clinical features,imaging manifestations,histological characteristics,treatment and prognosis were analyzed in combination with the literature.RESULTS The main symptoms of the 6 patients were nasal congestion accompanied by varying degrees of epistaxis.CT scans showed well-defined masses.The pathological features were perivascular spindle cell proliferation.The positive rate of SMA in immunohistochemistry was 100%,and the nuclear positive rate of β-catenin was 83%.All 6 patients underwent surgical treatment.No recurrence was observed during the 1-year to 10-year postoperative follow-up.CONCLUSION Pericellular tumor of the nasal cavity and paranasal sinuses is a rare tumor with low malignant potential.It lacks clinical specificity.Pathology and immunohistochemistry are the gold standards for diagnosis.Surgical treatment is an effective means of treatment,with a good prognosis,but long-term follow-up is required to monitor recurrence.
