Risk factors for stroke-associated pneumonia after endovasular treatment in acute anterior circulation ischemic stroke patients
10.16016/j.2097-0927.202506028
- VernacularTitle:急性前循环大血管闭塞性卒中患者血管内治疗后发生卒中相关性肺炎的危险因素分析
- Author:
Zhengwei CAI
1
;
Xiaoge ZHANG
;
Yang GAO
;
Meng ZUO
;
Lin DAI
;
Yujie QIN
;
Yu WANG
Author Information
1. 陆军军医大学(第三军医大学)第一附属医院神经内科
- Keywords:
acute ischemic stroke;
stroke-associated pneumonia;
endovascular treatment;
risk factors
- From:
Journal of Army Medical University
2025;47(20):2506-2511
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors for stroke-associated pneumonia(SAP)in acute ischemic stroke(AIS)patients after endovascular treatment(EVT).Methods A retrospective case-control trial was conducted on 426 AIS patients with large vessel occlusion(LVO)in anterior circulation admitted in the neurological departments from First Affiliated Hospital of Army Medical University and Zigong Third People's Hospital during January 2017 and April 2021.Based on SAP occurrence or not,they were divided into an SAP group and a non-SAP group.Demographic information(gender and age),TOAST stroke subtypes(large artery atherosclerosis type,cardiac embolism type,others),vascular risk factors(hypertension,hyperlipidemia,diabetes,atrial fibrillation,smoking,prior stroke history,smoking),and post-onset clinical data[dysphagia,LDL cholesterol,white blood cells,neutrophils,baseline and postoperative NIHSS scores,endovascular outcomes(mTICI grade 2b or 3),90-day good prognosis(mRS 0-1)]were collected and compared between the 2 groups.Multivariate logistic regression analysis was performed using the parameters with P<0.1 in univariate analysis as independent variables to investigate factors influencing SAP occurrence after EVT in AIS patients.Results Among the 426 participants,SAP occurred in 194 cases(45.5%).Multivariate logistic regression analysis revealed that admission white blood cell count(OR=1.125,95%CI:1.043～1.213,P=0.000 2),postoperative NIHSS score(OR=1.019,95%CI:1.001～1.037,P=0.041),and male(OR=1.687,95%CI:1.078～2.638,P=0.022)were associated with SAP occurrence after EVT in AIS patients.Conclusion Higher admission white blood cell count,elevated postoperative NIHSS score,and male gender are risk factors for SAP in AIS patients after EVT.These risk factors should be focused on clinical practice to control SAP incidence.
