Influencing factors of diabetic cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus
10.16781/j.CN31-2187/R.20240036
- VernacularTitle:2型糖尿病继发心脏自主神经病变的影响因素
- Author:
Lei WANG
1
;
Jingyun SONG
;
Cuilan HUO
;
Jin LU
Author Information
1. 海军军医大学(第二军医大学)第一附属医院内分泌科,上海 200433
- Keywords:
type 2 diabetes mellitus;
diabetic cardiovascular autonomic neuropathy;
influencing factors;
age factors
- From:
Academic Journal of Naval Medical University
2025;46(4):540-544
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the influencing factors of diabetic cardiovascular autonomic neuropathy(DCAN)secondary to type 2 diabetes mellitus(T2DM).Methods A total of 63 T2DM patients admitted to Department of Endocrinology in our hospital from Nov.1,2022 to Nov.30,2023 were enrolled.All patients were examined by cardiovascular autonomic nervous system.According to the results,they were assigned to DCAN group or non-DCAN group.Baseline data and laboratory parameters were recorded for each group.Logistic regression analysis was used to identify the influencing factors of DCAN secondary to T2DM,and receiver operating characteristic(ROC)curve analysis was used to study the predictive value of the influencing factors on DCAN.Results There were 32(50.79％)patients in the DCAN group and 31(49.21％)patients in the non-DCAN group.The mean age of the patients was significantly older in the DCAN group than in the non-DCAN group(P=0.002).Logistic regression analysis showed that age was a risk factor for DCAN secondary to T2DM(odds ratio=1.095,95％confidence interval 1.029-1.166,P=0.04).The ROC curve showed that the area under curve value of age predicting DCAN was 0.718,and the best diagnostic value was 58.5 years old,with a sensitivity of 0.719 and a specificity of 0.645.Conclusion Age is a risk factor for DCAN secondary to T2DM,and an increase in age leads to a higher positive rate of DCAN.
