Application of circulating tumor DNA in whole process management of patients with esophageal cancer:research progress
10.16781/j.CN31-2187/R.20220217
- VernacularTitle:循环肿瘤DNA在食管癌患者全程管理中的应用研究进展
- Author:
Tao LIU
1
;
Hai JIN
Author Information
1. 北京大学第一医院胸外科,北京 100034
- Keywords:
esophageal neoplasms;
circulating tumor DNA;
screening;
diagnosis;
clinical decision;
prognosis
- From:
Academic Journal of Naval Medical University
2025;46(2):244-252
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal cancer is one of the common malignant tumors,and its incidence in China is high.Effective prevention and control is a focus and challenge due to difficult prevention and late diagnosis.The development of liquid biopsy technology represented by circulating tumor DNA(ctDNA)provides new insights for early diagnosis,treatment evaluation and prognosis monitoring of esophageal cancer.ctDNA detection method has high specificity and sensitivity,which can be used in tumor screening and diagnosis,and has high application value in judging prognosis and guiding treatment.This article reviews the detection technology of ctDNA and the research progress in the diagnosis and treatment of esophageal cancer.
