The role of probiotics in prevention and treatment of heat stroke through modulation of the gut microbiota
10.16151/j.1007-810x.2025.05.008
- VernacularTitle:益生菌调节肠道菌群防治热射病的研究进展
- Author:
Jian-Yao YOU
1
;
Lei LI
;
Yi-Tong GONG
;
Yang-Yang CAO
;
Ji-Kuai CHEN
;
Shuo-Gui XU
Author Information
1. 海军军医大学第一附属医院急诊和创伤骨科,上海 200433;中国人民解放军东部战区总医院急诊医学科,江苏 南京 210002
- Keywords:
Heat stroke;
Gut microbiota;
Probiotics;
Intestinal barrier
- From:
Parenteral & Enteral Nutrition
2025;32(5):304-309
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the incidence of heat-related diseases has been on a steady upward trend,which is closely associated with environmental factors such as climate change and air pollution.Exposure to a hot environment and/or strenuous physical activities can progress to heat stroke(HS),an acute disease that can lead to death.Current research indicates that gut injury occupies the most crucial initiating position in the pathophysiological changes and pathogenesis of HS.Probiotics can reduce the incidence and mortality of HS through maintaining the health of the gut microbiota,regulating the intestinal immune system,and other effects.In addition,the gut microbiota can construct axis systems to interact with multiple organs such as the liver,lungs,and brain,which is of great significance for alleviating the damage to distant organs caused by HS.This paper reviews the regulation of the gut microbiota by probiotics to improve the intestinal heat tolerance ability and barrier function,aiming to provide references for the prevention and treatment of heat stroke in clinical practice.
