Optimizing micronutrient delivery in critically ill patients:challenges and opportunities
10.16151/j.1007-810x.2025.03.008
- VernacularTitle:优化危重症病人微量营养素的供给:挑战与机遇
- Author:
Yang HAN
1
;
Qing-Jie LIU
;
Qing-Song TAO
;
Jie WU
Author Information
1. 东南大学医学院,江苏 南京 210009
- Keywords:
Micronutrients;
Trace elements;
Vitamins;
Critical illness;
Nutritional monitoring
- From:
Parenteral & Enteral Nutrition
2025;32(3):171-178
- CountryChina
- Language:Chinese
-
Abstract:
Micronutrients are essential trace bioactive compounds that play a pivotal role in maintaining vital physiological functions,with particular significance in immune regulation among critically ill patients.Critical illness induces profound alterations in micronutrient metabolism,characterized by accelerated consumption and diminished reserves.This dysregulation is further exacerbated by malabsorption and various iatrogenic factors,creating substantial challenges in maintaining micronutrient homeostasis.As the significance of nutritional therapy in critical care continues to gain recognition,micronutrient supplementation has become an essential component of comprehensive treatment protocols.This review explores the dynamic changes in micronutrient status during critical illness and their associated immunomodulatory effects,while addressing key considerations for implementing targeted supplementation strategies.Furthermore,we evaluate contemporary methods for micronutrient monitoring and provide evidence-based guidelines to assist clinicians in optimizing nutritional support within critical care environments.
