Analysis of the combined application of enteral nutrition and Trocar puncture with a sump drain in the management of Crohn's disease complicated by intra-abdominal abscesses
10.16151/j.1007-810x.2025.03.004
- VernacularTitle:肠内营养联合Trocar穿刺置双套管引流治疗克罗恩病合并腹腔脓肿的应用分析
- Author:
Meng-Xuan LI
1
;
Wei-Jie LI
;
Dan-Dan XU
;
Song-Lin CHEN
;
Chao-Gang FAN
;
Yun ZHAO
Author Information
1. 南京医科大学附属明基医院肠瘘与腹腔感染中心,江苏 南京 210019
- Keywords:
Crohn's disease;
Enteral nutrition;
Abdominal abscess;
Trocar
- From:
Parenteral & Enteral Nutrition
2025;32(3):146-150
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy of enteral nutrition combined with trocar puncture with a sump drain in the treatment of Crohn's disease(CD)complicated by intra-abdominal abscess.Methods:A descriptive case series study was conducted.Clinical data of CD patients with intra-abdominal abscess who received enteral nutrition and trocar puncture with a sump drain at the Intestinal Fistula and Intra-abdominal Infection Center of Nanjing BenQ Hospital between June 2018 and December 2022 were retrospectively collected.Laboratory parameters,including white blood cell(WBC)count,C-reactive protein(CRP),and procalcitonin(PCT),were recorded at baseline(pre-puncture)and on days 1,3,and 7 post-puncture.Changes in clinical indicators before and after intervention were compared.Results:All 19 CD patients with intra-abdominal abscess successfully underwent CT-guided trocar puncture with a sump drain,with fistulography confirming the presence of intestinal fistula.No post-procedural complications,including puncture site infection,new-onset intestinal fistula or intra-abdominal hemorrhage,were observed.The median treatment duration was 58.3 days(range:14~300 days).10 patients achieved spontaneous healing while 9 eventually underwent surgical intervention for unresolved fistulas.Post-puncture WBC levels decreased significantly on days 1,3,and 7 compared to baseline(P<0.05).Serum CRP levels increased markedly on day 1 post-puncture(P<0.05)but declined significantly by days 3 and 7(P<0.05).No statistically significant difference was observed in serum procalcitonin levels before and after puncture(P>0.05).Conclusion:The combination of enteral nutrition and trocar puncture with a sump drain is safe,feasible,and effective for managing CD complicated by intra-abdominal abscess.