Study on the correlation between anemia and hypothyroidism in early pregnancy
10.16151/j.1007-810x.2025.03.003
- VernacularTitle:妊娠早期贫血和甲状腺功能减退的相关性研究
- Author:
Zhi-Ping SHI
1
;
Nuan FENG
;
Xiao-Ning LIU
;
Yu-Juan LIU
Author Information
1. 青岛大学附属妇女儿童医院营养科,山东 青岛 266034
- Keywords:
Early pregnancy;
Anemia;
Hypothyroidism
- From:
Parenteral & Enteral Nutrition
2025;32(3):142-145
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aimed to investigate the association between anemia and hypothyroidism during early pregnancy.Methods:We conducted a retrospective analysis of 3,165 pregnant women who registered at Qingdao Women and Children's Hospital from April 2021 to March 2022.Participants were categorized into a hypothyroidism group(n=177)and a euthyroid control group(n=2 988).Maternal demographic data,anemia-related markers(hemoglobin,Hb),and thyroid function parameters(FT3,FT4,TSH)were collected.Statistical analyses included independent t-tests,chi-square tests,Spearman correlation,and multivariate logistic regression.Results:The hypothyroidism group exhibited a significantly higher anemia incidence(10.17%vs 5.02%,P<0.05)and lower mean Hb levels(122.70±10.19 g/L vs 124.60±9.19 g/L,P<0.05)compared to controls.Spearman analysis revealed positive correlations between Hb and FT3(r=0.176)and FT4(r=0.051)(both P<0.05).Multivariate logistic regression identified anemia as an independent risk factor for hypothyroidism(OR=2.038,95%CI:1.202～3.455,P=0.008).Conclusion:Anemia in early pregnancy is associated with the risk of hypothyroidism.We recommend enhanced thyroid function screening and early intervention for anemic pregnant women to mitigate potential complications.
