Analysis of the influencing factors of early enteral nutrition-related diarrhea in severe patients with temporary ileostomy
10.16151/j.1007-810x.2025.01.008
- VernacularTitle:临时性回肠造口重症病人早期肠内营养相关性腹泻的影响因素分析
- Author:
Jia-Jia HU
1
;
Lu-Lu GU
;
Cui-Li WU
;
Xiang-Hong YE
;
Yan JIANG
;
Xin-Ying WANG
Author Information
1. 中国人民解放军东部战区总医院普通外科,江苏 南京 210002
- Keywords:
ICU;
Temporary ileostomy;
Early enteral nutrition;
Diarrhea;
Influencing factor
- From:
Parenteral & Enteral Nutrition
2025;32(1):48-53
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the influencing factors of diarrhea during early enteral nutrition(EEN)therapy in severe patients with temporary ileostomy.Method:A total of 154 patients with temporary ileostomy who received EEN in the Department of General Surgery,Jinling Hospital from November 2019 to November 2023 were included in this study.All patients were divided into two groups:the diarrhea group(n=43)and the non-diarrhea group(n=111).The clinical data of the patients were retrospectively collected and analyzed,and univariate analysis was performed to compare the differences between groups.The indicators with significant differences were subjected to multivariate logistic regression analysis to determine the influencing factors of diarrhea during EEN therapy in severe patients with temporary ileostomy.Result:Among the 154 patients,43 developed diarrhea during EEN therapy,with an incidence of 27.9%.Multivariate logistic regression analysis showed that enteral nutrition(EN)infusion rate(OR=6.342,P=0.001,95%CI:2.055～19.572),antibiotics type(OR=8.342,P=0.013,95%CI:1.577～44.119),mechanical ventilation(OR=7.011,P=0.001,95%CI:2.272～21.629),EN formulation type(OR=6.497,P=0.001,95%CI:2.177～19.392),and diabetes(OR=3.321,P=0.036,95%CI:1.080～10.215)were closely associated with EN-related diarrhea in severe patients with temporary ileostomy.Conclusion:There was a high incidence of diarrhea in severe patients with temporary ileostomy who received EEN.EN infusion rate,antibiotics use,mechanical ventilation,EN formulation type and diabetes were the influencing factors for presence of EEN-related diarrhea in the patients.Our data could provide a reference for preventing EEN-related diarrhea in severe patients with temporary ileostomy after surgery.
