Effect of ultra-early enteral nutrition intervention on the prognosis after severe craniocerebral injury surgery
10.16151/j.1007-810x.2024.06.002
- VernacularTitle:超早期肠内营养干预对重型颅脑损伤术后病人预后的影响
- Author:
Jia WANG
1
;
Xiu-Juan LIU
;
Hong ZHANG
;
Xin-Na FAN
;
Wen-Qi LU
;
Xiao-Yan ZHENG
;
Xiu-Mei LI
;
Ping LI
Author Information
1. 秦皇岛市第一医院,临床营养科,河北 秦皇岛 066000
- Keywords:
Ultra-early enteral nutrition;
Severe craniocerebral injury;
Intervention;
Prognosis
- From:
Parenteral & Enteral Nutrition
2024;31(6):329-333
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect of ultra-early enteral nutrition intervention on the prognosis of patients after severe craniocerebral injury surgery.Methods:A prospective study was conducted with 154 patients who underwent surgery for severe craniocerebral injury at the Neurosurgery Department of Qinhuangdao First Hospital.Patients were randomly divided into an experimental group and a control group using a random number table.Both groups received postoperative care in the Intensive Care Unit(ICU)with tracheal intubation retained within the postoperative 6 hours,and the head of the bed was elevated after 6 hours.The experimental group started ultra-early enteral nutritional support 6 hours after surgery,while the control group began early enteral nutritional support 24 hours after surgery.Total protein(TP),hemoglobin(Hb),albumin(ALB),prealbumin(PA),interleukin-6(IL-6),and C-reactive protein(CRP)were detected before intervention and on the 7th day post-intervention.The incidence of gastrointestinal complications,hospital-acquired infections,and prognostic indicators were recorded.Results:On the 7 days after intervention,TP,Hb,ALB and PA levels in the experimental group were significantly higher than those in the control group(P<0.05),and IL-6 and CRP levels were significantly lower than those in the control group(P<0.05).There was no significant difference in the incidence of abdominal distension,diarrhea,vomiting,and aspiration between the two groups(P>0.05).However,the incidence of hospital-acquired infections,ICU stay duration,total hospital stays,and mortality rate were all lower in the experimental group compared to the control group(P<0.05).Conclusion:Ultra-early enteral nutrition intervention can effectively improve the nutritional status and prognosis of patients after severe craniocerebral injury surgery.
