Research progress on the application of intrapleural pressure in mechanical ventilation treatment for shock patients
10.3969/j.issn.1671-8348.2025.11.035
- VernacularTitle:胸膜腔内压在休克患者机械通气治疗中的应用研究进展
- Author:
Jiayun ZHANG
1
;
Yong ZENG
Author Information
1. 重庆医科大学附属璧山医院急救部,重庆 402760
- Keywords:
mechanical ventilation;
shock;
intrapleural pressure;
circulatory system;
respiratory system
- From:
Chongqing Medicine
2025;54(11):2680-2685
- CountryChina
- Language:Chinese
-
Abstract:
Shock is a clinical syndrome caused by a sharp decrease in effective blood volume and tissue hypoperfusion from various etiologies.In the treatment of patients with shock,mechanical ventilation is one of the commonly used medical interventions.Mechanical ventilation directly affects intrapleural pressure(Ppl),which in turn has a direct impact on circulatory function,making it an important mediator in the pathophysio-logical interaction between mechanical ventilation and shock.Dynamic changes in Ppl affect respiratory and circulatory functions through mechanisms such as cardiopulmonary interactions.In the state of shock,imbal-ances in Ppl regulation can aggravate tissue hypoperfusion and organ dysfunction.The bidirectional effects of mechanical ventilation manifest in that positive pressure ventilation can improve oxygenation,but may also in-hibit venous return and increase ventricular afterload by raising mean Ppl.This article reviews the physiologi-cal significance of Ppl and its dynamic changes under shock conditions,and analyzes the clinical application and challenges of individualized mechanical ventilation strategies based on Ppl monitoring in patients with shock.
