Correlation study between red blood cell distribution width and dialysis hypotension and arteriovenous fistula thrombosis
10.3969/j.issn.1671-8348.2025.11.025
- VernacularTitle:红细胞分布宽度与透析低血压、内瘘血栓形成的相关性研究
- Author:
Ying HUANG
1
;
Lixin JIN
;
Jinghong LEI
Author Information
1. 北京航天总医院肾内科,北京 100071
- Keywords:
red blood cell distribution width;
hypotension during dialysis;
hemodialysis;
arteriovenous fistula;
thrombosis
- From:
Chongqing Medicine
2025;54(11):2626-2630,2637
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between red blood cell distribution width(RDW)and intradialytic hypotension(IDH)as well as arteriovenous fistula thrombosis.Methods A total of 110 patients who received hemodialysis treatment at the Blood Purification Center of Beijing Aerospace General Hospital from January 1,2021,to June 1,2022,were selected as the study subjects.According to whether intradialytic hypotension(IDH)occurred,the patients were divided into the IDH group(n=40)and the non-IDH group(n=70).The occurrences of arteriovenous fistula thrombosis during dialysis,baseline data,laboratory indica-tors,and IDH event records of the two groups were recorded to analyze the relationship between RDW and IDH as well as arteriovenous fistula thrombosis.Results The average age of the IDH group was(66.05±12.42)years,higher than that of the non-IDH group at(50.96±14.50)years(P<0.05).The RDW in the IDH group was 16.24%±1.36%,higher than that in the non-IDH group at 14.17%±1.04%(P<0.05).Be-fore IDH correction,RDW levels increased progressively from the mild,moderate,to severe hypotension groups,with statistically significant differences between groups(P<0.05);12 weeks after IDH correction,there were no statistically significant differences in RDW levels among the groups(P>0.05).Logistic regres-sion analysis showed that RDW and IDH events were independent risk factors for arteriovenous fistula throm-bosis(HR>1,P<0.05).The AUC for RDW in predicting IDH events was 0.880(95%CI:0.816 to 0.944).Con-clusion Patients with higher RDW levels have a higher probability of developing IDH,and RDW and IDH events are independent risk factors for arteriovenous fistula thrombosis.
