Effect of ECMO combined with IABP on the efficacy and prognosis of patients with acute myocardial infarction complicated by cardiogenic shock
10.3969/j.issn.1671-8348.2025.11.018
- VernacularTitle:ECMO联合IABP对急性心肌梗死合并心源性休克患者的疗效及其对预后的影响
- Author:
Jie JIN
1
;
Jun XU
Author Information
1. 嘉兴市第一医院急诊科,浙江 嘉兴 314001
- Keywords:
extracorporeal membrane oxygenation;
intra-aortic balloon pump;
acute myocardial infarc-tion;
cardiogenic shock;
prognosis
- From:
Chongqing Medicine
2025;54(11):2588-2593
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effects and the influence on prognosis of extracor-poreal membrane oxygenation(ECMO)combined with intra-aortic balloon pump(IABP)on patients with a-cute myocardial infarction(AMI)complicated by cardiogenic shock(CS).Methods A total of 113 patients with AMI complicated by CS who were admitted to the hospital from June 2020 to November 2023 were se-lected as the study subjects.They were randomly divided into an observation group(n=58)and a control group(n=55)using a random number table method.The observation group received ECMO combined with IABP treatment,while the control group received IABP treatment.Treatment-related indicators,hemodynam-ics,incidence of complications,and prognosis were compared between the two groups.Results Compared with the control group,the observation group had higher rates of norepinephrine use and epinephrine use,larger va-soactive drug dose,longer duration of vasoactive drug use and IABP application time,higher successful wea-ning rate,longer ICU stay,and lower peak creatine kinase levels,with statistically significant differences(P<0.05).At 24 and 72 hours after treatment,systolic blood pressure,diastolic blood pressure,and mean arterial pressure in both groups were higher than before initiation and were higher in the observation group than in the control group,while heart rate and lactate levels were lower than before initiation and were lower in the obser-vation group than in the control group,with statistically significant differences(P<0.05).Compared with the control group,the observation group showed higher incidences of puncture-site lower limb ischemia,acute kid-ney injury,pulmonary infection,gastrointestinal bleeding,and a higher 1-year cumulative survival rate[50.00%(29/58)vs.30.91%(17/55)],with statistically significant differences(P<0.05).Conclusion Com-pared with IABP alone,ECMO combined with IABP significantly improves hemodynamics and increases sur-vival in patients with AMI complicated by CS,but also increases the risk of complications.
