Research progress of 3D bioprinting technology carrying mesenchymal stem cells in the field of periodontal tissue regeneration
10.3969/j.issn.1671-8348.2025.10.032
- VernacularTitle:搭载间充质干细胞的3D生物打印技术在牙周组织再生领域中的研究进展
- Author:
Jiajia CHENG
1
;
Guangsheng CHEN
;
Li GAO
Author Information
1. 遵义医科大学口腔医学院,贵州遵义 563000;遵义医科大学附属口腔医院牙周科,贵州遵义 563000
- Keywords:
mesenchymal stem cells;
3D bioprinting;
periodontal tissue;
regenerative medicine;
tissue engineering
- From:
Chongqing Medicine
2025;54(10):2419-2425
- CountryChina
- Language:Chinese
-
Abstract:
Periodontal tissue diseases are common oral diseases.Although traditional mechanical de-bridement therapy can control inflammation,it is difficult to achieve complete regeneration of periodontal tis-sues.In recent years,research and applications of combining 3D bioprinting technology with mesenchymal stem cells(MSCs)have rapidly developed in the field of periodontal tissue regeneration.This combined ap-proach provides a novel strategy for periodontal tissue regeneration by constructing a biomimetic microenvi-ronment and promoting cell proliferation and differentiation.This article reviewed the types of 3D bioprinting technology,the characteristics of bioink materials,the sources of MSCs,and their application progress in peri-odontal tissue regeneration.Additionally,it analyzed the current technical bottlenecks and clinical translation challenges,aiming to provide references for future research and clinical applications.
