Comparison of the therapeutic effects of antimicrobial photodynamic therapy combined with subgingival scaling and root planing in the treatment of chronic periodontitis
10.3969/j.issn.1671-8348.2025.10.022
- VernacularTitle:抗菌光动力疗法联合龈下刮治和根面平整术治疗慢性牙周炎的疗效对比
- Author:
Pengfei YANG
1
;
Chengli XIONG
;
Chengrong LIU
Author Information
1. 丰都县人民医院口腔科,重庆 408200
- Keywords:
chronic periodontitis;
antimicrobial photodynamic therapy;
subgingival scaling treatment;
root planing technique;
efficacy
- From:
Chongqing Medicine
2025;54(10):2366-2370
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effect of antimicrobial photodynamic therapy(aPDT)combined with subgingival scaling and root planing(SRP)on chronic periodontitis.Methods A total of 198 patients with chronic periodontitis who were diagnosed and treated in the Department of Stomatology of the hospital from August 2023 to April 2024 were selected as the study subjects.A randomized block design was used to divide the patients into a control group(n=98)and an experimental group(n=98).The control group received oral education and SRP treatment,while the experimental group received oral education and aPDT+SRP treatment.The depth of periodontal pocket probing(PD),positive rate of bleeding probing(BOP),bleeding index(BI),and plaque index(PLI)were compared of patients before and after 6 weeks of treatment,and the levels of tumor necrosis factor-α(TNF-α)and IL-6 in gingival crevicular fluid were meas-ured.Results After treatment,the proportion of patients with PLI grade 0 and 1 in the experimental group was higher than the control group(x2=30.640,P＜0.001).The PD of the experimental group was lower than that of the control group(t=9.420,P＜0.001).The AL of the experimental group was lower than that of the control group(t=4.495,P＜0.001).The proportion of patients with grade 0 and grade 1 of BI index in the experimental group was higher(x2=48.839,P＜0.001).The average levels of IL-6 and TNF-α in the ex-perimental group were lower than those in the control group(P＜0.001).Conclusion SRP+aPDT therapy not only effectively improves periodontal clinical indicators in patients with chronic periodontitis,but also sig-nificantly reduces the levels of local inflammatory factors,which is worthy of promotion and application.
