Impact of different eating ways on survival of patients with esophageal perforation after esophageal squamous cell carcinoma radiotherapy
10.3969/j.issn.1671-8348.2025.09.017
- VernacularTitle:不同进食方式对食管鳞癌放疗后食管穿孔患者生存的影响
- Author:
Chuanshan YAO
1
;
Lei MA
;
Quanxiao XU
;
Chenlu FENG
Author Information
1. 南阳市第一人民医院肿瘤科,河南南阳 473010;河南省胃癌耐药及临床转化工程研究中心,河南南阳 473010
- Keywords:
esophageal squamous cell carcinoma;
esophageal perforation;
eating method;
survival;
nutri-tional status
- From:
Chongqing Medicine
2025;54(9):2098-2102
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of different eating methods(tube feeding,esophageal stents,intravenous nutrition)on the survival of the patients with esophageal perforation after esophageal squamous cell carcinoma radiotherapy.Methods A retrospective analysis was conducted on the clinical data of 61 inpatients with esophageal perforation after esophageal squamous cell carcinoma radiotherapy in Nanyang Municipal First People's Hospital from January 2013 to December 2022.According to the different perforation sites,they were divided into the esophagomediastinal fistula group(n=38)and esophagotracheal fistula group(n=23).The Kaplan-Meier method was used to evaluate the survival situation of the patients with different eating patterns,and the nutritional status of the patients one in 1 month after esophageal perforation was eval-uated.Results All patients died within 12 months(median survival time was 4.3 months).The 3-month and 6-month survival rates of the patients with tube feeding were 81.2％and 37.5％respectively,those of the pa-tients with esophageal stents were 63.2％and 15.8％,and those of the patients with intravenous nutrition were 40.0％and 0 respectively,and the differences were statistically significant(P＜0.05).In the esophago-mediastinal fistula group,the 3-month and 6-month survival rates of the patients with tube feeding were 85.0％and 45.0％respectively,those of patients with esophageal stents were 75.0％and 16.7％respectively,and those of the patients with intravenous nutrition were 50.0％and 0 respectively,and the differences were statistically significant(P＜0.05).In the esophagotracheal fistula group,the 3-month and 6-month survival rates of the patients with tube feeding were 75.0％and 25.0％respectively,those of the patients with esopha-geal stents were 42.9％and 14.3％respectively,and those of the patients with intravenous nutrition were 25.0％and 0 respectively,and the differences were not statistically significant(P＞0.05).The nutritional sta-tus score of the patients with intravenous nutrition was significantly higher than that of the patients with tube feeding and esophageal stents(P＜0.05),but there was no statistically significant difference in the nutritional status score between the patients with tube feeding and the patients with esophageal stents(P＞0.05).Conclusion Com-pared with esophageal stents and intravenous nutrition,tube feeding could achieve relatively higher survival rates and better nutritional status.
