Application of 3D printed individualized tissue compensators in intensity-modulated radiotherapy of vulvar cancer
10.3969/j.issn.1671-8348.2025.09.010
- VernacularTitle:3D打印个体化组织补偿物在外阴癌调强放疗中的应用
- Author:
Yuping GUO
1
;
Shuming SONG
;
Li XIE
;
Jie GAO
;
Aihemaiti XIAYILA
;
Tuoheti ZULIPIYAMU
;
Lin HE
;
Chengqiong TANG
Author Information
1. 新疆医科大学附属肿瘤医院妇科放疗一病区,乌鲁木齐 830000
- Keywords:
vulvar cancer;
3D printing;
conventional tissue compensators;
personalized tissue compensa-tors;
radiotherapy
- From:
Chongqing Medicine
2025;54(9):2054-2058
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of 3D printed individualized tissue compensators on the dose of the radiotherapy target area and the radiotherapy accuracy in intensity-modulated radiotherapy for vul-var carcinoma.Methods Twenty patients with vulvar cancer who visited this hospital from December 2022 to December 2024 were selected as the research subjects and divided into the control group and 3D group accord-ing to the random number table method,10 cases in each group.The control group used the conventional tis-sue compensators,while the 3D group used the 3D printed individualized tissue compensators.The dosimetric results of the target area and normal tissues were compared between the two groups.Results Compared with the control group,the maximum dose[(5 501.00+22.12)cGy vs.(5 659.60+84.59)cGy],average dose[(5 203.60+52.45)cGy vs.(5 258.70+42.95)cGy]and dose of 2％target volume[(5 360.30+63.70)cGy vs.(5 408.90+91.90)cGy]in the 3D group were lower,and the homogeneity index(0.12+0.01 vs.0.13+0.02)and conformity index(1.16+0.05 vs.1.23+0.04)were better,and the differences were statistically significant(P＜0.05).There was no statistically significant difference in dose of 30％clinical target volume of the bladder and rectum between the two groups(P＞0.05).During and after radiotherapy,among 20 cases,4 cases presented with grade 3 skin reactions,which were wet peeling,with 2 cases in each of the two groups.The remaining 16 cases had the grade 1 to 2 skin reactions.Conclusion In intensity-modulated radiotherapy for vulvar carcinoma,the dose distribution of 3D-printed personalized tissue compensators is superior to that of conventional organizational compensators.
