Research progress on the application of opioid-free anesthesia in comfortable diagnosis and treatment
10.3969/j.issn.1671-8348.2025.08.033
- VernacularTitle:去阿片化麻醉在舒适化诊疗中应用的研究进展
- Author:
Haochen WANG
1
;
Yingchao GUAN
;
Xiaodong WANG
Author Information
1. 滨州医学院第二临床医学院,山东 烟台 264000
- Keywords:
opioid-free anesthesia;
comfort diagnostic and treatment;
respiratory depression;
hypoten-sion;
esketamine;
dexmedetomidine
- From:
Chongqing Medicine
2025;54(8):1952-1957
- CountryChina
- Language:Chinese
-
Abstract:
Comfortable diagnosis and treatment aims to ensure that patients can receive medical exami-nations and treatments safely and comfortably.The traditional anesthesia plan often relies on opioid,but the latter is prone to cause risks such as respiratory depression,hypotension,and hypoxemia.Opioid-free anesthe-sia(OFA),as a multimodal strategy,significantly reduces opioid-related adverse reactions by combining non-opioid drugs(such as esketamine,dexmedetomidine,lidocaine)and techniques(such as surface anesthesia,re-gional block).This article systematically reviews the application progress of OFA in comfortable diagnosis and treatment such as painless gastroscopy and colonoscopy,endoscopic retrograde cholangiopancreatography,bronchoscopy and induced abortion.
