Research progress on the mechanism of myocardial infarction induced by particulate matter and ultrafine particles
10.3969/j.issn.1671-8348.2025.08.032
- VernacularTitle:颗粒物与超微颗粒致心肌梗死机制的研究进展
- Author:
Kenan WU
1
;
Song ZOU
;
Xianyong FU
Author Information
1. 重庆医科大学国际医学院,重庆 400016
- Keywords:
myocardial infarction;
particulate matter;
ultrafine particles;
oxidative stress;
inflammatory reaction
- From:
Chongqing Medicine
2025;54(8):1945-1951
- CountryChina
- Language:Chinese
-
Abstract:
Particulate matter is an important component of air pollution,with sources including indus-trial emissions and motor vehicle exhaust.With rapid industrialization and urbanization,air pollution has be-come increasingly severe,drawing widespread attention to the health hazards of particulate matter,particularly its effects on the cardiovascular system.Particulate matter is categorized by particle size into coarse particles,fine particles,and ultrafine particles.Due to their extremely small size and large specific surface area,ultrafine particles can penetrate deep into the lungs and enter the bloodstream,exerting significant impacts on the cardi-ovascular system.This review examines recent literature on the relationship between particulate matter and cardiovascular diseases,explores the potential mechanisms by which particulate matter-especially ultrafine particles-triggers myocardial infarction,and suggests potential future research directions.