Progress in the application of new acid-suppressing drug Tegoprazan in the treatment of Helicobacter pylori
10.3969/j.issn.1671-8348.2025.07.034
- VernacularTitle:新型抑酸药物替戈拉生在幽门螺杆菌感染治疗中的应用进展
- Author:
Yan FAN
1
;
Shengtao LIAO
;
Lin LYU
;
Chuanfei LI
;
Yuru LIN
;
Zhechuan MEI
Author Information
1. 重庆医科大学附属第二医院消化内科,重庆 400010
- Keywords:
Helicobacter pylori;
tegoprazan;
potassium-competitive acid blocker
- From:
Chongqing Medicine
2025;54(7):1724-1728
- CountryChina
- Language:Chinese
-
Abstract:
Tegoprazan is a novel potassium-competitive acid blocker with long-lasting and potent acid-suppressing effects,showing favorable efficacy in many acid-related diseases.In eradicating Helicobacter pylori(Hp)infections,tegoprazan-based regimens are noninferior to proton pump inhibitor(PPI)regimens in terms of efficacy,and are well tolerated and safe.In this article,we review the pharmacological mechanism,clinical studies on Hp eradication regimens,and safety of tegoprazan to provide a reference for the selection of Hp e-radication regimens.