Comparison of the short-term efficacy of NOSES and CLS in the treatment of rectal cancer
10.3969/j.issn.1671-8348.2025.07.018
- VernacularTitle:NOSES与CLS在直肠癌治疗中的短期疗效对比
- Author:
Jie LIANG
1
;
Mingwang LI
;
Wei PENG
;
Chunming LIU
Author Information
1. 浙江省人民医院毕节医院胃肠外科,贵州 毕节 551600
- Keywords:
rectal cancer;
natural orifice specimen extraction surgery;
short-term outcomes;
laparoscopy
- From:
Chongqing Medicine
2025;54(7):1631-1636
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the short-term clinical outcomes between Natural Orifice Specimen Extraction Surgery(NOSES)and conventional laparoscopic surgery(CLS)for rectal cancer.Methods Clini-cal data of 120 patients with rectal cancer admitted to this hospital from May 2021 to May 2023 were retro-spectively analyzed.They were divided into a NOSES group and a CLS group(60 cases each)according to sur-gical approach.Short-term efficacy of both surgical approaches was analyzed.Results The NOSES group had longer operative time,shorter postoperative hospital stay,and lower incision infection rate than the CLS group(P<0.05).Serum CRP levels in the NOSES group were lower than those in the CLS group on postoperative days 1,3,and 5(P<0.05).VAS scores in the NOSES group were lower than those in the CLS group at 6 hours and days 1-7 postoperatively(P<0.05).The proportion of patients requiring additional dezocine anal-gesia was lower in the NOSES group at 6 hours and days 1-4 postoperatively(P<0.05).CEA levels gradu-ally decreased over time in both groups(P<0.05),but showed no significant intergroup difference(P>0.05).Conclusion Compared with CLS,NOSES has advantages of less postoperative pain,faster recovery,and shorter hospital stay for rectal cancer patients.
