Molecular mechanisms and treatment research progress of olfactory dysfunction in patients with chronic sinusitis
10.3969/j.issn.1671-8348.2025.06.034
- VernacularTitle:慢性鼻窦炎患者嗅觉功能障碍的分子机制及治疗研究进展
- Author:
Dong WANG
1
;
Wenlong LUO
Author Information
1. 重庆医科大学附属第二医院耳鼻咽喉头颈外科,重庆 400010;达州市中心医院耳鼻咽喉头颈外科,四川 达州 635000
- Keywords:
chronic rhinosinusitis;
olfactory dysfunction;
molecular mechanism;
biologic therapy
- From:
Chongqing Medicine
2025;54(6):1476-1482
- CountryChina
- Language:Chinese
-
Abstract:
Chronic rhinosinusitis(CRS)is a chronic inflammatory disease of the sinus mucosa,with up to 83%of CRS patients suffering from olfactory dysfunction(OD),which seriously affects the life quality of patients.However,due to the difficulty in obtaining tissue from the olfactory epithelium,the mechanisms of inflammatory OD remain poorly understood.Therefore,a deeper understanding of the mechanism of OD oc-curence in CRS patients is crucial for improving their quality of life and prognosis.This article focused on the mechanisms underlying the development and progression of CRS-related OD,as well as current clinical inter-ventions.
