Risk factors for chronic critical illness of patients with septic shock in the ICU
10.3969/j.issn.1671-8348.2025.05.017
- VernacularTitle:ICU脓毒症休克患者发展为慢性危重症的危险因素分析
- Author:
Maiqing SHI
1
;
Fuhai JI
;
Yang WANG
;
Xu WANG
;
Yu YAN
;
Qinghong HUANG
;
Jun CHEN
Author Information
1. 苏州大学附属第一医院麻醉手术科,江苏苏州 215006
- Keywords:
intensive care unit;
septic shock;
organ failure;
chronic critical illness;
quick recovery
- From:
Chongqing Medicine
2025;54(5):1143-1146,1150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors for the development of chronic critical illness(CCI)in septic shock patients in the intensive care unit(ICU).Methods A retrospective analysis was conducted on 102 sepsis shock patients admitted to the ICU of the hospital from August 2018 to May 2023.According to their clinical dates,they were divided into CCI group(n=60)and rapid recovery(RR)group(n=42).Multi-ple logistic regression analysis was perform to identify independent risk factors for developing CCI in septic shock patients,and construct their receiver operating characteristic(ROC)curves to evaluate their predictive value for CCI.Results The prolonged duration of hypernatremia(OR=1.770,95％CI:1.147-2.731,P=0.010)and low acute physiology and chronic health(APACHEⅡ)scores(OR=1.212,95％CI:1.025-1.433,P=0.025)were independent risk factors for CCI in ICU septic shock patients.The occurrence of acute gastrointestinal injury(OR=0.060,95％CI:0.011-0.341,P=0.002)and peak blood sodium levels during ICU(OR=0.812,95％CI:0.662-0.995,P=0.044)were protective factors.Conclusion For septic shock pa-tients,special attention should be paid to its related independent risk factors and protective factors to improve the prognosis of septic shock patients.
