Real-world study of glycerin enema for preoperative bowel preparation in benign anorectal diseases
10.3969/j.issn.1671-8348.2025.04.021
- VernacularTitle:甘油灌肠剂在肛肠良性疾病术前肠道准备中应用的真实世界研究
- Author:
Yingqian LI
1
;
Yuanbo ZHANG
;
Changlu WANG
;
Jingxiang LI
Author Information
1. 北京中医药大学第三附属医院肛肠科,北京 100029
- Keywords:
real-world study;
benign anorectal diseases;
bowel preparation;
glycerin enema;
polyethy-lene glycol;
application effect
- From:
Chongqing Medicine
2025;54(4):910-914
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of glycerin enema in preoperative intestinal preparation for anorectal benign diseases.Methods A total of 74 patients with benign anorectal diseases admitted to the anorectal department of our hospital from September 2023 to December 2023 were selected as the study ob-jects.According to different preoperative intestinal preparation methods,they were divided into glycerol group(n=30)and compound polyethylene glycol electrolyte powder(PEG-EP)group(n=44).The glycerol group was treated with glycerol enema to clean the intestine,and the PEG-EP group was treated with PEG-EP ene-ma before operation.Adverse reactions,defecation frequency,intestinal cleanliness,intestinal preparation tol-erance,first postoperative defecation time and bowel quality were observed and compared between the two groups.Results Propensity score was used for 1∶1 matching,and 25 patients were included in the two groups after PSM.The main adverse reactions were abdominal pain in the glycerol group and nausea,abdomi-nal distension and diarrhea in the PEG-EP group.There was no significant difference in the incidence of ad-verse reactions between the two groups(P＞0.05).Compared with the PEG-EP group,the number of bowel movements after bowel preparation in the glycerol group was less,the intestinal preparation tolerance rate was higher,and the time of first postoperative bowel movement was earlier,with statistical significance(P＜0.05).Conclusion Glycerin enema has more advantages than oral PEG-EP in preoperative intestinal prepara-tion for anorectal benign diseases.
