Preliminary clinical exploration of endoscopic ultrasound combined with modified endoscopic mucosal resection in the treatment of rectal neuroendocrine tumors
10.3969/j.issn.1671-8348.2025.04.018
- VernacularTitle:超声内镜联合改良内镜下黏膜切除术在直肠神经内分泌肿瘤治疗中的效果分析
- Author:
Ping LUO
1
;
Aimin LIU
;
Zhiqiang YI
;
Qiaomu LUO
;
Sha WEI
;
Jing KUANG
;
Jing TANG
Author Information
1. 重庆大学附属涪陵医院消化内科,重庆 408099
- Keywords:
rectal neuroendocrine tumors;
endoscopic ultrasound;
endoscopic mucosal resection;
endo-scopic submucosal dissection;
effect analysis
- From:
Chongqing Medicine
2025;54(4):893-897
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical feasibility and safety of endoscopic ultrasonography(EUS)combined with modified endoscopic mucosal resection(EMR)in the treatment of rectal neuroendo-crine tumors(RNETs).Methods A total of 48 patients diagnosed with RNETs by colonoscopy in the depart-ment of gastroenterology in this hospital from December 2021 to June 2023 were selected as the study objects.Patients were randomly divided into the study group(EUS combined with modified EMR,n=16),the control 1 group(traditional EMR,n=16)and the control 2 group[endoscopic submucosal dissection(ESD),n=16].The operation time,R0 resection rate and postoperative complications of each group were observed.Endoscop-ic ultrasonography was followed up 3 and 6 months after surgery to determine whether there was any recur-rence.Results The operative time of the study group[(17.813±0.379)min]was significantly shorter than that of the control 2 group[(36.250±3.296)min],the difference was statistically significant(P＜0.05),but compared with the control 1 group[(16.375±1.996)min],there was no significant difference(P＞0.05).The incidence of complications in the study group(6.2％)was significantly lower than that in the control 2 group(37.5％),the difference was statistically significant(P＜0.05).while the incidence of complications in the study group was not significantly higher than that in the control 1 group(12.5％,P＞0.05).R0 removal rate in the study group(93.8％)was significantly higher than that in the control 1 group(62.5％)and the control 2 group(75.0％),the difference was statistically significant(P＜0.05).Conclusion EUS combined with modified EMR has more advantages than EMR and ESD in the treatment of RNETs,and has certain fea-sibility and safety,which is convenient for clinical application.
