Research advances in T2-type asthma biomarkers
10.3969/j.issn.1671-8348.2025.03.035
- VernacularTitle:T2型哮喘相关生物标志物的研究进展
- Author:
Haiqin LIU
1
;
Hao TANG
Author Information
1. 海军军医大学第二附属医院呼吸与危重症医学科,上海 200433
- Keywords:
type 2 asthma;
biomarkers;
epigenetics;
evaluation
- From:
Chongqing Medicine
2025;54(3):760-764
- CountryChina
- Language:Chinese
-
Abstract:
Asthma,one of the most prevalent chronic immune disorders worldwide,is classified into type 2(T2)and non-T2 asthma based on airway inflammation patterns.Patients with different phenotypes ex-hibit variations in clinical manifestations,disease severity,and therapeutic sensitivity.Currently,various treat-ment modalities including biologics have been developed for refractory asthma,most demonstrate better thera-peutic responses in T2 asthma.This highlights the critical importance of timely and accurate identification of T2 asthma and assessment of its severity through highly specific and sensitive biomarkers,which can guide precision treatment strategies to enhance therapeutic efficacy and reduce economic burdens.This article sum-marizes recent advancements in T2 asthma-related biomarkers to provide references for precision diagnosis and personalized treatment.