Analysis of clinical characteristics and risk factors of vancomycin-resistant Enterococcus faecium isolated from urine
10.3969/j.issn.1671-8348.2025.03.022
- VernacularTitle:尿液分离耐万古霉素屎肠球菌患者的临床特征及尿路感染的危险因素分析
- Author:
Mengmin YE
1
;
Pingjuan LIU
;
Siting YI
Author Information
1. 中山大学附属第一医院医学检验科,广州 510080
- Keywords:
vancomycin-resisitant Enterococcus faecium;
urinary tract infectionl;
clinical characteris-tics;
risk factors
- From:
Chongqing Medicine
2025;54(3):683-688
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics and risk factors of vancomycin-resistant En-terococcus faecium(VRE-fm)isolated from urine,and to provide a scientific basis for the prevention and treatment of VRE-fm in clinic.Methods The clinical data and drug sensitivity results of 60 patients with VRE-fm strains isolated from urine in this hospital from January 2017 to June 2023 were retrospectively ana-lyzed.The patients were divided into the infection group(n=46)and the non-infection group(n=16)accord-ing to the status of urinary tract infection.Univariate and multivariate logistic regression were used to analyze the risk factors of urinary tract infection caused by VRE-fm.Results Among the 60 patients with VVRE fm strain isolated from urine,43 cases(71.7%)were female,36 cases(60.0%)were≥65 years old,42 cases(70.0%)had a history of indignant catheter,and the median length of hospitalization was 26.5 days.The re-sults of in vitro VRE-fm drug sensitivity test showed that the resistance rate of Teicolanin was 95%,and the resistance rate of linezolid and tigacycline were 1.7%.Multivariate logistic regression analysis showed that u-rinary sludge white blood cell count＞5/HP was an independent risk factor for VRE-fm urinary tract infec-tion(P＜0.05).Conclusion Urine-isolated VRE-fm infections were more common in female,older patients and were significantly associated with a history of indwelling catheters.
