Application and challenge of controlled low central venous pressure in liver resection surgery

VernacularTitle:控制性低中心静脉压在肝脏切除术中的应用和挑战
Author: Qian TANG ¹ ; Bing CAI ; Guangmin XU
Author Information

1. 成都中医药大学医学与生命科学学院,成都 610075
Keywords: liver resection surgery; low central venous pressure; acute kidney injury; prognosis
From: Chongqing Medicine 2025;54(2):528-531
CountryChina
Language:Chinese
Abstract: Hepatic resection and liver transplantation usually adopt the controlled low central venous pressure(CLCVP)technique and liver blood flow blocking technique,which can reduce hepatic venous pres-sure,thus effectively reduce intraoperative blood loss and blood transfusion,as well as decrease the risk of sur-gery,therefore have been widely used in clinical practice.However,intraoperative hypotension may occur when applying CLCVP and hepatic portal blockade,which increases the risk of acute kidney injury,myocardial injury and neurologic complications,moreover increases the postoperative mortality rate of the patients.The goal-di-rected fluid therapy(GDFT)is a novel fluid infusion measure that optimizes the vital organ perfusion,reduces the risk of monitoring central venous pressure and effectively improves the patient's prognosis.This article discussed the use of CLCVP technique in hepatic resection,challenges and the advantages of GDFT in periop-erative fluid management.