Radiofrequency ablation and parathyroidectomy for treating secondary hyperparathyroidism:a meta analysis
10.3969/j.issn.1671-8348.2025.02.033
- VernacularTitle:射频消融与甲状旁腺切除治疗继发性甲状旁腺功能亢进的meta分析
- Author:
Wu XIAO
1
;
Wei CHEN
;
Yong YANG
;
Hua XU
Author Information
1. 江西省人民医院/南昌医学院第一附属医院甲状腺头颈外科 330006
- Keywords:
radiofrequency ablation;
parathyroidectomy;
secondary hyperparathyroidism;
meta analysis
- From:
Chongqing Medicine
2025;54(2):484-488,495
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy and safety of radiofrequency ablation(RFA)and para-thyroidectomy(PTx)for treating secondary hyperparathyroidism(SHPT)by meta analysis.Methods The studies on the clinical efficacy of RFA and PTx in the treatment of SHPT were retrieved from Pubmed,Em-base,Cochrane Library,CNKI,Wanfang,CBM,and VIP databases.The retrieval time was from the establish-ment of the database to December 2023.The literatures were screened according to the inclusion and exclusion criteria,the data were extracted and the literature quality was evaluated.The meta analysis of the included da-ta was performed by using RevMan5.3.Results Finally,7 articles with 415 patients were finally included,in-cluding 185 cases in the RFA group and 230 cases in the PTx group.The results of meta analysis showed:there was no statistically significant difference in the incidence rate of postoperative hoarseness between the two groups(RR=0.96,95%CI:0.65-1.42,P=0.83),the incidence rate of postoperative hypocalcemia in the RFA group was significantly lower than that in the PTx group(RR=0.58,95%CI:0.42-0.81,P<0.05),and the hospital stay duration in the RFA group was shorter than that in the PTx group(MD=-3.32,95%CI:-5.28--1.36,P<0.05),and there was no statistically significant difference in the levels of PTH,blood calcium and blood phosphorus in postoperative 1,3,6 months between the two groups(P>0.05).Conclusion Com-pared with PTx,RFA for treating SHPT could reduce the incidence rate of postoperative complications,short-en the length of hospital stay,and achieve the same therapeutic effect.
