Efficacy comparison of glenohumeral intraarticular injection of platelet-rich plasma and sodium hyaluronate in treatment of glenohumeral joint osteoarthritis
10.3969/j.issn.1671-8348.2025.02.018
- VernacularTitle:盂肱关节内注射富血小板血浆与玻璃酸钠治疗盂肱关节骨关节炎的疗效比较
- Author:
Guangyuan LIU
1
;
Baotao CAO
;
Jiangli ZHANG
;
Xiao FAN
;
Menghui WU
;
Jinhui LIU
Author Information
1. 河北省石家庄市第三医院:关节一科,石家庄 050000
- Keywords:
glenohumeral joint osteoarthritis;
platelet-rich plasma;
sodium hyaluronate;
joint pain and function
- From:
Chongqing Medicine
2025;54(2):393-397,404
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect of sodium hualuronate(SH)and platelet rich plasma(PRP)injections in the treatment of glenohumeral joint osteoarthritis(GJO).Methods Sixty-three patients with GJO were randomly assigned to receive either PRP(PRP group,n=29)or SH(SH group,n=34)injec-tions.The injections were administered into the glenohumeral joint under ultrasound guidance.The patients were assessed by the Visual Analogue Scale(VAS),American Shoulder and Elbow Surgeons(ASES)score and modified University of California(UCLA)shoulder joint score before injection and at 1,6,12 months of injection.Results There were no statistically significant differences in the general data between the two groups(P>0.05).Compared with before injection,the VAS scores at 1,6,and 12 months after injection in the two groups were significantly decreased(P<0.05).The VAS score at 12 months after injection in the SH group was significantly increased(P<0.05).The VAS score at 12 months after injection in the PRP group was lower than that in the SH group(P<0.05).The ASES scores showed a significant increase at 1 month after injection compared to before treatment(P<0.05),moreover the ASES scores at 6 months after injection in the PRP group were higher than those in the SH group(P<0.05).Compared with before injection,the modified UCLA shoulder joint scores at 1,6 months after injection in the two groups were significantly in-creased(P<0.05),moreover the scores of the modified UCLA shouder joint scores at 6 months after injec-tion in the PRP group were higher than those in the SH group(P<0.05).Conclusion Pain relief in intraar-ticular injection of PRP in GJO patients is more significant than intraarticular injection of SH,moreover PRP is significantly superior to SH in improving the shoulder joint function of the patients.
