Research progress in potential influence of intestinal flora on post-stroke dysphagia complicating pulmonary infection
10.3969/j.issn.1671-8348.2025.01.041
- VernacularTitle:肠道菌群对脑卒中后吞咽障碍并发肺部感染潜在影响的研究进展
- Author:
Xiaohua ZHAO
1
;
Renyi ZHANG
;
Feng YE
;
Shiling TAN
Author Information
1. 重庆市铜梁区人民医院康复医学科,重庆 402560
- Keywords:
stroke;
dysphagia;
intestinal flora;
migration;
lung infection;
aspiration
- From:
Chongqing Medicine
2025;54(1):224-230,236
- CountryChina
- Language:Chinese
-
Abstract:
The probability of pulmonary infection in stroke patients with dysphagia will be multiplied,which may endanger the life of the patients,and is a major problem to be solved urgently in clinic.Stroke and dysphagia can both lead to intestinal flora disorders,destroy the intestinal barrier function and create the con-ditions for the migration of opportunistic pathogenic bacteria from the intestinal tract to the lungs,which may trigger or exacerbate the symptoms of pulmonary infections in the patients.Based on the theory of"microbe-gut-lung"axis,this article reviews the related studies on the disorder of intestinal flora caused by dietary chan-ges after stroke and dysphagia,and then leads to the migration of intestinal flora to the lungs,resulting in pul-monary infections,as well as the potential impact of aspiration on the pulmonary infections complicating dys-phagia after stroke.The potential impact of aspiration on post-stroke swallowing disorders and concomitant lung infections.In order to explore the potential mechanism of recurrent pulmonary infections in the patients with post-stroke dysphagia from the perspective of parenteral dissemination of intestinal flora,and to provide new ideas for subsequent clinical interventions.
