Research advance in influence of trace element selenium on autoimmune thyroid diseases
10.3969/j.issn.1671-8348.2025.01.040
- VernacularTitle:微量元素硒对自身免疫性甲状腺疾病影响的研究进展
- Author:
Suqing BAO
1
;
Lijun DUAN
Author Information
1. 天津市第一中心医院内分泌科,天津 300192
- Keywords:
autoimmune thyroid disease;
selenium;
thyroid hormone;
Graves'disease;
Hashimoto's thyroiditis
- From:
Chongqing Medicine
2025;54(1):219-223
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune thyroid disease(AITD)is a disease in clinical work,which is developed by the combined action of immune dysfunction and environmental abnormalities and other factors based on the genet-ic factor.In recent years,with the continual improvement of living level,people are more concerned about their health,the detection rate of AITD has increased.Studies find that the occurrence of AITD is closely related to the abnormal immunity mediated by T lymphocytes.As an organ-specific disease,AITD mainly includes Graves'disease(GD)and Hashimoto thyroiditis(HT).Selenium is an essential trace element in human body.In recent years,it has been found that the selenium preparations are involved in immune regulation,and have the functions for maintaining immune homeostasis,improving chronic inflammation and alleviating im-mune disorders of thyroid tissue.This paper reviews the research progress on the effects of selenium on AI-TD,aiming to provide the new ideas for the prevention and treatment of AITD.
