Effects of EEG biofeedback treatment on sleep quality and autonomic nervous function in patients with depression
10.3969/j.issn.1671-8348.2025.01.023
- VernacularTitle:脑电生物反馈治疗对抑郁症患者睡眠质量及自主神经功能的影响
- Author:
Jiangnan DENG
1
;
Xinwu YE
;
Feifei ZHAO
Author Information
1. 温州市第七人民医院普通精神科,浙江温州 325000
- Keywords:
EEG biofeedback;
escitalopram;
depression;
sleep disorder;
sleep quality;
autonomic nervous function
- From:
Chongqing Medicine
2025;54(1):127-131,137
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of EEG biofeedback on the sleep quality and autonomic nervous function in the patients with depression sleep disorder.Methods A total of 98 inpatients with depres-sive sleep disorder treated in this hospital from January 2020 to August 2021were selected as the study sub-jects and divided into the study group and control group according to the random number table method,49 ca-ses in each group.The control group adopted the escitalopram treatment,and the study group was combined with EEG biofeedback on this basis.The Hamilton Depression Scale(HAMD)score,Pittsburgh Sleep Quality Index(PSQI)score,subjective insomnia symptom score,heart rate variability(HRV)index,serum neuropep-tide Y(NPY)and 5-hydroxytryptamine(5-HT)levels and the incidence rate of adverse reactions before treat-ment and in 3 months of treatment were compared between the two groups.Results The total effective rate of the study group was significantly higher than that of the control group(95.92％vs.81.63％),and the difference was statistically significant(P＜0.05).After 3 months of treatment,the HAMD,PSQI,subjective insomnia symptom score and PNN50 in both groups were decreased compared with those before treatment,moreover the study group was lower than the control;the levels of SDNN,SDANN,LF,HF and serum NPY and 5-HT were increased compared with those before treatment,moreover the study group was higher than the control group,and the differences were statistically significant(P＜0.05).There was no statistically sig-nificant difference in the incidence rate of adverse reactions between the two groups(14.29％vs.10.20％,P＞0.05).Conclusion EEG biofeedback combined with escitalopram could significantly improve the depres-sive symptoms and sleep quality in the patients with depression,regulate the autonomic nervous function and increase serum NPY and 5-HT levels.
