Advances in application of techniques related to study of neural circuits in pain
10.3969/j.issn.1671-8348.2024.23.023
- VernacularTitle:疼痛的神经环路研究相关技术应用进展
- Author:
Jianye WANG
1
;
Yanqin BIAN
;
Zheng XIANG
;
Shaoqiang PEI
;
Yiwei CHENG
;
Jun SHEN
;
Lianbo XIAO
Author Information
1. 上海中医药大学附属光华医院,上海 200052;上海市中医药研究院中西医结合关节炎研究所,上海 200052
- Keywords:
pain;
neural circuits;
regulatory mechanisms;
technology application;
review
- From:
Chongqing Medicine
2024;53(23):3651-3656
- CountryChina
- Language:Chinese
-
Abstract:
Pain is an uncomfortable and emotional experience associated with,or similar to,real or po-tential tissue damage.However,far from being a purely physiological sensation,pain involves complex emo-tional and neuromodulatory mechanisms.The pain neural circuit is a complex biological system,covering the multi-level structure of the central nervous system from peripheral neurons to the cerebral cortex,thalamus,a-mygdala and dorsal horn of the spinal cord,participating in the perception,conduction,and regulation of pain signals,involves multiple molecular and cellular interactions to build a comprehensive pain perception process.In recent years,the field of pain neural circuit research has used a variety of scientific and technological tools to provide the theoretical and technical support for the in-depth understanding and treatment of pain.This article aims to provide a comprehensive research status quo for the scholars in related fields and new ideas for clinical pain research and treatment by combing the application of different technologies in the study of pain neural circuits.
