Research advances in programmed cell death mechanisms underlying myocardial fibrosis
10.13406/j.cnki.cyxb.003904
- VernacularTitle:程序性细胞死亡在心肌纤维化中的研究进展
- Author:
Tingting QI
1
;
Xin ZHANG
;
Li BAI
;
Wen MA
;
Wenxiu MA
Author Information
1. 内蒙古科技大学包头医学院,包头 014000
- Keywords:
myocardial fibrosis;
programmed cell death;
research advances
- From:
Journal of Chongqing Medical University
2025;50(11):1601-1608
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis and progression of myocardial fibrosis(MF)are modulated by diverse cytokines and signaling pathways.Studies in recent years have revealed an extremely close association between MF evolution and programmed cell death(PCD)modali-ties,including apoptosis,autophagy,pyroptosis,necrosis,ferroptosis,and cuproptosis.This article reviews the characteristics of MF and distinct PCD modalities,with particular emphasis on cutting-edge discoveries elucidating PCD in the field of MF,hoping to pro-vide a theoretical-level reference basis for the in-depth exploration and clinical intervention of MF.
