Research advances in acromegaly comorbid with diabetes mellitus
10.13406/j.cnki.cyxb.003948
- VernacularTitle:肢端肥大症合并糖尿病的研究进展
- Author:
Siyu ZHANG
1
;
Huiwen TAN
Author Information
1. 四川大学华西医院内分泌代谢科,成都 610041
- Keywords:
acromegaly;
glucose metabolism;
growth hormone;
insulin-like growth factor-1
- From:
Journal of Chongqing Medical University
2025;50(10):1303-1308
- CountryChina
- Language:Chinese
-
Abstract:
Abnormal glucose metabolism is one of the common complications of acromegaly.Patients with acromegaly have a signifi-cantly higher prevalence rate of abnormal glucose metabolism compared with the normal population,and the patients with acromegaly and diabetes mellitus(DM)have significantly higher prevalence rates of tumor and cardiovascular diseases.Growth hormone and insulin-like growth factor-1 have different effects on glucose metabolism in patients with acromegaly,and surgeries or drugs(such as somatostatin receptor ligands)for the treatment of acromegaly may disturb or affect glucose metabolism in the body,which requires fur-ther clarification.This article reviews the research advances in the diagnosis and treatment of abnormal glucose metabolism in patients with acromegaly,in order to identify optimal treatment strategies and achieve better management of acromegaly and related metabolic complications.
